As CSE inhibits autophagosome maturation and degradation in macrophage like cells, and consequent intracellular and extracellular concentrations of galectin-8 are altered leading to the activation of pro-inflammatory signalling cascades, the galectin-8/NDP52 pathway may prove to be a novel therapeutic target in COPD
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Bernice being, well, Bernice, responds like Roddy Piper by taking the fire extinguisher and blasting the woman with it at point-blank range
