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E-cigarettes, like traditional cigarettes, can cause nicotine addiction

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Some studies suggest that heavy marijuana use during adolescence could be linked to changes in brain structure and function

Mappin-Kasirer B, et al

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These have been found to contain a complex mixture of chemical compounds, including the highly water-soluble nicotine, a toxic compound [3] along with approximately environmentally persistent 4,000 different compounds like polycyclic aromatic hydrocarbons, heavy metals, arsenic, and tar leading to the release of toxic substances into aquatic environments and posing a threat to aquatic organisms and water sources [46]