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A short video showing a woman without a hijab burning a photograph of Irans Supreme Leader, Ayatollah Ali Khamenei, to light a cigarette has spread rapidly across social media, becoming one of the most striking protest images linked to the latest wave of unrest associated with Iran

doi:10.1136/bmj.h2757

More than anything, she is there when your heart breaks and fills for another person. ABC News' Pierre Thomas, Mike Levine, Luke Barr, Kerem Inal, Chris Looft,Jared Kofsky, Josh Margolin and Matt Foster contributed to this report.

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Throughout the decades that followed, the cigarette rolling machine design and use has transformed profoundly in response to the changing tastes and requirements of the tobacco market