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A phase 3 experiment is currently evaluating chemotherapy with or without ADI-PEG20 (NCT02709512) in 386 patients following promising clinical outcomes in a phase 2 experiment

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clarified that acute secondhand exposure to vaping aerosol has been shown to result in non-significant changes in levels of toxicant biomarkers

Final Thoughts Determining an exact puff-to-cigarette nicotine equivalence is challenging due to individual differences in vaping and smoking behaviors