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Mechanistically, this focal accumulation is thought to result from the synergistic effects of cytokines such as IL-4, IL-33, and TSLP, along with chemokines such as CCL17 and CCL22 within the inflamed tissue microenvironment (65, 66)

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NIH: National Institute of Dental and Craniofacial Research [Learn More in MedlinePlus] Smoking What are the health effects of smoking