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It has to do with how smoking affects your immune responses, your social behaviors during smoking, and the changes smoking causes to your bodys tissues and functions

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The accuracy of The PLCO m2012 model alone, which predicts a 6-year risk of lung cancer among current or former smoker based on individual characteristics, was significantly lower, at 80%

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Thus, maternal smoking during pregnancy is associated with epigenetic changes that may modulate the offsprings risk for deleterious neurobehavioral and neurodevelopmental outcomes