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Some of the most noted effects that nicotine has on the body include: The increased risk of cardiovascular, respiratory, and gastrointestinal disorders Decreased immune response Increase in oxidative stress Increase in cancer risk Does nicotine reduce anxiety

"For our calculations, we assumed an adult who smokes one pack of cigarettes per day beginning at age 21, when a person can legally purchase tobacco products in the U.S

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Furthermore, in a 2021 survey of over 20,000 middle and high school students, over 50% used ONPs along with another tobacco product, potentially leading to very high levels of nicotine consumed [2]