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Other differences were a greater fibrotic reaction and faster development of emphysema in DBA/2 mice (three months versus six months in C57 mice), and more extensive goblet cell metaplasia and immunohistochemical reaction for IL-4, IL-13, and MUC5AC (a secreted mucin) in C57 mice

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The most recent study, published in the journal Basic & Clinical Pharmacology & Toxicology, surveyed thousands of adults admitted to a New York City emergency room

6 Social norms play a role in continued smoking