Your doctor will advise you not to take ciprofloxacin if you are taking the following medications: There can also be interactions between ciprofloxacin and the following medicines: Medications used to treat mental illnesses such as some antidepressants (Cymbalta) and antipsychotics (Clozaril, Zyprexa) Some nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin, Aleve, Naprosyn) Certain medicines used to treat irregular heartbeat (Pacerone, Norpace, Betapace, Sorine, Sotylize) Ropinirole (Requip) Diuretics or water pills Antibiotics like azithromycin (Zithromax, Zmax), clarithromycin (Biaxin, in Prevpac), and erythromycin (Eryped, Eryc, E.E.S.) Medications that contain caffeine (Vivarin, Excedrin) Phenytoin (Dilantin, Phenytek) Pentoxifylline (Pentoxil) Sildenafil (Viagra, Revatio) Cyclosporine (Neoral, Gengraf, Sandimmune) Insulin and oral medications used to treat diabetes (Amaryl, Glucotrol, DiaBeta) Tolazamide and tolbutamide Methotrexate (Trexall, Rasuvo, Otrexup) Probenecid (Probalan) Zolpidem (Ambien) Theophylline (Theo-24, Elixophyllin, Uniphyl) This list does not describe all possible ciprofloxacin interactions
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