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In the 1880s, while Duke was beginning to machine-roll all his cigarettes, he saw that growth rates in the cigarette industry were declining

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Impact of polycyclic aromatic hydrocarbon exposure on cognitive function and neurodegeneration in humans: a systematic review and meta-analysis

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If the plants have been treated with pesticides, workers may suffer greater exposure to these pesticides than they would while performing agricultural work in other crops treated with pesticides.[69] In addition, jobs where workers directly handle pesticide-treated plantssuch as topping or harvesting leaves by handcan increase exposure, particularly in the absence of effective protective gear and handwashing