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In addition, differences in sample, methodology, and confounders representativeness also contribute to the different PAFs between studies

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For example, lung and colon cancers from people who smoke tend to have a specific mutation in the ras oncogene or p53 tumor suppressor gene (i.e., mostly a G to T nucleotide base substitution) and that this mutation is likely due to direct interaction of the carcinogen in smoke benzo[]pyrene with DNA

Clapton continued to record a number of successful solo albums and songs over the next several decades, including a 1974 cover of Bob Marley's "I Shot the Sheriff" (which helped reggae reach a mass market), [7] the country-infused Slowhand album (1977) and the pop rock of 1986's August

doi: 10.1093/ntr/ntv23 Fairchild, A