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Among the 1.14 billion smokers in the world, the vast majority started using tobacco in adolescence or early adulthood 1, 2 , which explains the intense interest of both the public health community and the tobacco industry in youth

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doi: 10.1016/j.jhep.2020.11.035 20 SteinbergSECampbellCLHillmanRS

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These results suggest that high doses of and long-lasting exposure to CS are needed to induce irreversible miRNA alterations, which may be involved in CS-related diseases