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Brain imaging studies show that regular e-cigarette use can alter activity in brain regions involved in addiction and cognitive control, including the prefrontal cortex and limbic system
In survey years 2014 and 2015, sex was asked as Are you Male or Female? In survey year 2016, the question was revised and asked as Sex Assigned to You at Birth, On Birth Certificate [15]
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Participants who were using any of these products daily were classified as daily smokers, while those who were using them not every day but at least once in the last 30 days were classified as non-daily smokers
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