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In patients with high nicotine dependence who had radical resection of lung cancer, preoperative smoking cessation within 3 weeks of surgery resulted in worse postoperative pain outcomes and greater opioid requirement than earlier smoking cessation [78]

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But before you panic, partygoers: Spiegelhalters argument doesnt have much to do with holiday noshing per se -- the paper noted explicitly that the microlife risks do not apply to single exposures (i.e., that blowout office party) and dont take into account differences between individuals

The success of treatment greatly depends on how early its caught

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