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Deke Slayton, had been selected from among 110 of the nations top military test pilots to train as astronauts for Project Mercury, the first phase of the U.S

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Photochemical & Photobiological Sciences, 20 (12), 15731584

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Trouble is that NRT has a 90% plus failure rate because the drug is being delivered very slowly to the brain (orally or through the skin) and from the users point of view lacks the pleasure of inhaling

It might be more difficult for smokers to stay alert and focused, which would affect their daily routines