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The team discovered that nicotine exposure moderately reduced the amount of aromatase in the brain. The researchers believe that their study is the first to show this inhibitory effect on aromatase production [] in humans. For the first time, we can see that nicotine works to shuts down the estrogen production mechanism in the brain of women

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Accordingly, the structural and functional disorder of airway epithelial barrier may be a key link in the occurrence and development of COPD [5, 15]