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Thus determining the overall smoking-related mortality rate in a population can pose a challenge, as all of these diseaseseven lung cancer to a relatively minor degreeappear in nonsmokers as well, making it difficult to determine the percentage of deaths that can be attributed to smoking

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It is a defective design because the holes may be blocked during smoking but not during machine measurement of smoke constituents

[59] The risk of early death is anticipated to be similar to that of smokeless tobacco