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Steps 25: modeling doseresponse RR of smoking on the selected health outcomes Of the six steps proposed by Zheng et al

And so its entirely possible that if youre looking at a sample thats mostly older individuals, you might just expect any sample like that to have fewer smokers than the overall general population. Murray noted the older age of patients in these studies (median age of 71 in Italy)

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This mechanism operates independently of sun exposure, which is why smoker lips develop even in people who avoid the sun