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COMMENTARY Nicotinamide is marketed as a nicotine substitute for e-cigarettes In October 2023, the major e-cigarette supplies wholesaler, Nicotine River, known for sales of bulk nicotine, solvents, and flavors, began sales of a nicotine substitute with the brand name Nixamide, a name trademarked by the company Ready Mix Naturals, LLC, and with the main active ingredient being Nicotinamide 4

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Modern sensitive methods can detect very small traces of chemicals with no impact on health

Look for transparency in ingredients, compliance with local safety standards, nicotine strengths that match your needs, and positive reviews from real users

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We focus on transparency and purity, unlike many e-liquids that rely on artificial fillers and chemical flavoring agents