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a study showed a reduction of forced expiratory volume in 1 s (FEV1) in never smokers when compared with FEV1 following acute and passive e-cigarette exposures 20 and low toxicity of e-cigarettes in vitro 21 , while others find higher toxicity and inflammatory effects of e-cigarettes in vitro 22-27 and in vivo 24,28,29

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Lynch who smoked his first cigarette at the age of eight is now suffering from emphysema (a chronic lung condition) so severe that he requires supplementary oxygen simply to walk across a room

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