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It has been found an increase in CV symptoms, such as tachycardia and arrhythmia, expected because of the sympathomimetic effects of nicotine, but no increase in major CV events (death, myocardial infarction, stroke) [8]

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Additionally, the rise of convenience and discreet use among younger consumers propels the demand for smokeless tobacco products in North America

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Cytisine overdosing is similar to nicotine intoxication and produces nausea, vomiting, clonic seizures, tachycardia, mydriasis, headache, fatigue, respiratory pump failure