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have found that the expression of LC3-II and Beclin-1/BECN1 were upregulated in leuk-1 cells upon CS stimulation and this upregulation was in a concentration- and time-dependent manner [78], suggesting that CS exposure could trigger the autophagy of human oral epithelial cells

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Although there is a surprising level of demand for nicotine-free vapes , most people use vape juice with nicotine because they want to replace the nicotine in cigarettes