Store in a cool, dry place away from direct sunlight and out of reach of children
Due to their large surface area, continuous exposure to environmental toxins and pathogens, and high metabolic needs related to the production of surfactants and ion transport, AECs are highly dependent on complete mitochondrial quality control mechanisms to maintain cell function and viability (Malsin and Kamp, 2018)
Not only that but there was a time when a British chaplain gave away Bibles together with Woodbine cigarettes
In addition, accumulation of dysfunctional mitochondria due to failed mitophagy promotes a senescence-associated secretory phenotype in AECs, further amplifying pro-fibrotic signaling (Malsin and Kamp, 2018
however, a recent analysis in a UK cohort found a similar positive relationship with tea, suggesting it could apply more generally to caffeine
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