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This smoke can be toxic

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The charcoal is the source of most of the carbon monoxide and polycyclic aromatic hydrocarbons (such as benzo[a]pyrene) found in waterpipe smoke

Prenatal exposure to cigarette smoke has been associated with lower DNA methylation of CYP1A1 at CpG sites surrounding the xenobiotic response-element, which is a major transcriptional enhancer of CYP1A1 expression (Suter et al., 2010)

In the case of DEGs, which were decreased in expression after e-cigarette exposure, the trend was significant at 24 h after CS exposure (Figs

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