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Closure: Lace up

Zyban is an antidepressant and Chantix is a medication that blocks the effects of nicotine in the brain and eases withdrawal symptoms so users can more easily quit smoking and maintain their abstinence on a long-term basis

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Scientific studies have suggested that other cannabinoids like CBD may also play a significant role in its psychoactive effects

But if you smoke, you throw the whole thing wildly out of balance in favor of the negative

In contrast, our MR analysis employed SNPs as IVs to mitigate these biases and yielded more accurate estimates of potential causality, leveraging a much larger GWAS sample of European ancestry (COPD, n=468475)