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Fifteen Massachusetts communities restrict nicotine pouches to adult-only facilities, according to the New England Convenience Store and Energy Marketers Association

Demand varies significantly by tobacco variety

There is some concern over the ingredients in e-liquid: propylene glycol, vegetable glycerin, and flavorings

On average, the cost of smoking is substantially higher than the cost of vaping

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The Mayo Clinic states that genetics "may influence how receptors on the surface of your brain's nerve cells respond to high doses of nicotine delivered by cigarettes," which could mean that, due to genetic inheritance, once people start smoking, some are more likely than others to subsequently continue the habit