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Similarly, total reflection X-ray fluorescence spectrometry (TRXFS) has been employed for heavy metals characterization in e-liquids, demonstrating short analysis time, and simultaneous multi-element determination [45]

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And here is the research to back it up: 1

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They found that PNE rats treated with methamphetamine showed significant enhancements in motor behavior, conditioned hyperactivity, and exhibited greater conditioned response of hyperactivity as compared to saline controls