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In the future, we plan to include crude and partially adjusted risk estimates in our analyses to fully incorporate all available risk estimates, to model the adjusted covariates in a more comprehensive way by mapping the adjusted covariates across all studies comprehensively and systematically, and to develop methods to evaluate additional forms of potential bias

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Notably, sputum M1 macrophage frequencies did not associate with impaired lung function, unlike neutrophil counts (Supplementary Fig

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